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Growth Factor Serum

Professional Strength

Price: $ 69.99

Size: 1.0 oz / 30 ml


Availability: In Stock

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Cosmetic Dermatology

Discover Solvaderm's Professional Strength Products For Healthier And More Beautiful Skin.

Replexagen is a fast-acting, revolutionary serum designed to radically reduce multiple signs of aging. The state-of-the-art formula delivers a synergistic blend of peptides including five growth factors which are molecularly identical to those found in the human placenta. Through regular application of these powerful peptides, skin becomes more resilient to the damaging effects of aging, becoming smoother, wrinkle-free and totally rejuvenated. Collagen production is boosted, giving the skin a plump, youthful appearance while thin, fragile tissue structure becomes denser, firmer and fully nourished. Replexagen's technologically-advanced blend of professional-strength ingredients have shown to improve the appearance of crow's feet around the eyes by up to 21% in just 4 weeks and immediately increase levels of moisture in the skin by 83% after just one application. By boosting the body's antioxidant levels, damage from free radical activity is reduced and the skin regains its healthy, youthful glow.



Paraben freePerfume freePROFESSIONAL STRENGTH

The numerous peptides and nourishing ingredients found in the Replexagen formula fight all signs of aging in the skin including fine lines, wrinkles and dry, dull skin. By working synergistically, this unique blend of active ingredients combined in one powerful serum has multiple benefits for the user which include the following:

  • Makes aging, fragile skin more resistant to damage by increasing its structure and density
  • Reduces the damaging effects of free radicals in the system by significantly increasing levels of antioxidants
  • Provides life-giving growth factors that are molecularly identical to those found in the human placenta, promoting cell regeneration, elasticity and skin reparation
  • Quickly relieves dryness by boosting levels of moisture in the skin upon application
  • Reinforces the capillaries and improves the skin's circulation for a noticeably brighter, glowing complexion
  • Supports the health of the skin for the long term by fortifying and firming delicate tissue structure
  • Slows the aging process and improves the skin's ability to protect itself against further signs of aging

Sources To Support The Claims Made for Replexagen

Penning A [webpage on the Internet] Biomimetics: beauty ingredients that mimic bio functions. GCI Magazine. 2013. Oct 14, [Accessed August 23, 2015]. p. 3.

Varani J, Dame MK, Rittie L, et al. Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. Am J Pathol. 2006;168(6):1861-1868

Fabi S, Sundaram H. The potential of topical and injectable growth factors and cytokines for skin rejuvenation. Facial Plast Surg. 2014;30(2):157-171.

Fitzpatrick RE, Rostan EF. Reversal of photodamage with topical growth factors: a pilot study. J Cosmet Laser Ther. 2003;5(1):25-34.

Schouest JM, Luu TK, Moy RL. Improved texture and appearance of human facial skin after daily topical application of barley produced, synthetic, human-like epidermal growth factor (EGF) serum. J Drugs Dermatol. 2012;11(5):613-620.

Florin L, Maas-Szabowski N, Werner S et al. Increased keratinocyte proliferation by JUN-dependent expression of PTN and SDF-1 in fibroblasts. J Cell Sci 2005; 118: 1981-9.

Kamoun A, Landeau JM, Godeau G et al. Growth stimulation of human skin fibroblasts by elastin-derived peptides. Cell Adhes Commun 1995; 3: 273-81.

Replexagen's peptide-rich serum can be used on all areas of the facial skin including the forehead, cheeks, jowls and eye area. It is particularly beneficial where expression lines develop due to repetitive muscle movements.

Ingredients: Purified Water, Glycerin, Acetyl Glutamine, Lecithin, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, sh-Polypeptide-11, Bacillus/Soybean/Folic Acid Ferment Extract, 3-Aminopropane Sulfonic Acid, Calcium Hydroxymethionine, Acetyl Hexapeptide-30, Acetyl Hexapeptide-8, Sodium Hyaluronate, Ammonium Acryloyldimethyltaurate/VP Copolymer, Caprylyl Glycol, Polysorbate-20, Pentylene Glycol, Butylene glycol, 1,2-Hexanediol, Arginine, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate.

Biomimetic Peptides

A breakthrough in skincare technology, Biomimetic Peptides are an essential part of the advanced Replexagen formula and play an important role in the treatment of aging, vulnerable skin. Replexagen contains five vital growth factors - Epidermal Growth Factor (EGF) - helps to regenerate skin cells while boosting hydration levels to combat dryness Insulin-like Growth Factor (IGF) - works towards reversing multiple signs of aging such as fine lines and deep-set wrinkles around the delicate eye area and promotes healing and the production of skin-plumping collagen Acidic Fibroblast Growth Factor (AFGF) - rejuvenates underlying cells and regenerates aging skin tissue, resulting in firmer, smooth skin that is more resilient against damaging stressors Basic Fibroblast Growth Factor (BFGF) - boosts the skin's elasticity, making it more resistant to aging while also reducing the appearance of scars and blemishes Vaso-Endothelial Growth Factor (VEGF) - provides essential nutrition for aging cells and maintains optimal oxygen supply for healthy, radiant skin


The Neuropeptides used in Replexagen affect cellular function in several skin-benefitting ways. By disrupting communication between the cells, these potent peptides safely limit muscle movement, leading to a drastic reduction in the formation of expression lines and wrinkles. Skin is relaxed, appearing smoother, refreshed and overall more youthful in appearance. By having this effect on cellular function, these neuropeptides work synergistically with the other key active ingredients in Replexagen to slow signs of aging over the long term and promote optimal skin renewal.

Oligo Elements

Mature, aging skin benefits greatly from the addition of Oligo Elements which maintain enzyme reactions while boosting antioxidants in the body for free radical-fighting capabilities. As part of Replexagen's revolutionary antiaging formula, Oligo Elements support collagen production, restoring firmness, texture and tone. With sagging and dullness eliminated, the skin regains its youthful plumpness and radiance.

Directions Of Use

Cleanse the skin and gently pat dry. Apply a small amount of Replexagen to the fingertips and, using a circular motion, massage into the skin paying extra attention to the forehead and areas around the eyes and mouth. Replexagen should be applied twice daily as part of the morning and evening skincare routine. For best results, use Replexagen in conjunction with other products in the Solvaderm range such as Dermpura Skin Balancing Cleanser and Maxatone Clarifying Biohydrating Toner.

*Disclaimer: The FDA has not evaluated these statements and the supplement product is not intended to diagnose, treat, cure or prevent any disease. Remember to read our labels and ingredient lists carefully and follow the appropriate directions for use. If you have a specific allergy or sensitivity, do not use ingredients that may trigger a reaction. An allergy patch test is recommended if there is any doubt or history of skin reactions. Discontinue use if a reaction occurs.*

Summary Of Customer Ratings & Reviews

  • Overall Rating
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  1. I am so happy with this serum

    Angria M. Age: Above 50

    I’ve been using Replexagen serum for a few weeks now. I have noticed my acne and fine lines lesions and older scars seem to be softening and sloughing off. Overall I’m satisfied with this serum is helping me to get rid of the ugly acne lesions I’ve learned to live with. I’m 53 and I highly recommend it, if you’re looking to maintain and keep a wrinkle free face.

    Rating: 5
  2. Great Result Great customer service!

    Jesse R. Age: 46-50

    This serum has reduced my fine lines, wrinkles and sagging skin. It has produced amazing results that everyone is noticing. I bought it now for about a month and great price, and will continue to use the product because it works so well. The customer service was excellent.

    Rating: 5
  3. Great Results!!

    Leia Age: Above 50

    I am 53 and I didn’t like what was happening to my face with all the sagging and dullness going on. I was looking forward to it. I happened upon this Replexagen, and I made the purchase. I have been completely impressed with the results! My hairstylist actually commented after her hand touched my face and said that my skin was so firm and wanted me to reveal my secret. I see her once a month and started using this product shortly after my last appointment. I had definitely noticed that my skin was looking and feeling better, but to have someone else notice was great! Best purchase of a skin care product I have made…EVER!

    Rating: 5
  4. Great product! Feels lovely on the skin

    Nichole D. Age: 41-45

    Very happy with this Serum. I was experiencing increasing fine lines. But finally searched and found this Replexagen serum. After using it for a few days I could see a change for the better, and now after a month I continue to see good but real improvement, and I believe it is that the skin is replenishing collagen. Also, I have sensitive skin and this has not caused ANY problems for me. My skin really looks better since I started using it. Loving the results so far-smoother and clearer skin. Will purchase again!

    Rating: 5
  5. Very happy with my skin!

    Margaret A. Age: 46-50

    My skin looks so much better now that I started using this serum. I am 49 years old and I am starting to get wrinkles along with an occasional breakout of acne. It’s horrible. However, since I started using this, my skin has almost been “stable” without any breakouts! It did not make my skin peel or too dry. My wrinkles are even less visible. Very, very, happy!! THANK YOU!

    Rating: 5
  6. Get rid of aging spots

    Aimee C. Age: Above 50

    I was pleasantly surprised with Replexagen. I’m 62 yrs old and trying to get rid of some aging spots. I can’t expect miracles at my age, but slowly seeing some changes. I was very impressed with the care and instructions for using this product. My niece works at a dermatologist office and she was impressed with the tips and concerns you sent with the product I’m using. Care and Consideration.

    Rating: 5
  7. Amazing product for a great price

    D. Miller Age: 41-45

    Amazing product for a great price. I am 42 and woke up recently to the terrible discovery of my first fine line and decided to add a Replexagen serum to my routine. I started adding this to my routine every other day as the company suggested. Not only has my line faded, but my skin is brighter and more even toned in general and I swear my pores have tightened. For the price, it cannot be beat.
    It feels so good and seems to smooth my skin. I will be ordering again.

    Rating: 5
  8. Quality Product for aging skin

    Kristen Age: Above 50

    I am going to be 65 years soon. People tell me that I look like I’m in my early 50s. Yes, I have good genes. But as soon as I saw my skin sagging, I tried this serum. I love it. I believe it works. My facial skin tightened up a little and it is sagging much less than my same-aged peers! Thanks for making Replexagen serum available to us

    Rating: 5
  9. I LOVE this product

    Shea Age: 46-50

    I am a 46 year old woman who has struggled with wrinkles, fine lines and scars for a few years. I have tried so many different products and nothing worked. My fine lines and scars were affecting my self-esteem and making me depressed. This serum is the first product that has ever really worked for me. My skin is absolutely amazing. I would recommend Replexagen to everyone.

    Rating: 5
  10. Serum leaves my skin feeling plumper and smoother

    T. Jenan Age: 46-50

    I am so in love with this serum! I’ve been using this serum morning and night for over a month now and I’ve already noticed big improvements in my skin! This serum leaves my skin feeling plump and smooth, and helps to calm any redness that I may be experiencing. I’m so excited to continue using this and see the results in a few months from now!

    Rating: 5
  11. My favorite nightly serum!

    Alyssa B. Age: 41-45

    Replexagen is really one of my favorite serums I’ve used. I am using it twice daily as part of the morning and evening skincare routine and I love that it rejuvenates skin. It really moisturizes my skin and it has really helped my lines. My favorite part about it reduces my blemishes and scars. My skin looks more fresh and well taken care of. I really like it!

    Rating: 5
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    For Best Results

    Combine Zeroblem with these products to achieve the best results.

    Solvaderm Ace Ferulic
    Ace - Ferulic
    Solvaderm Maxatone