STEMUDERM
Anti-Wrinkle Dermatological Treatment
Professional Strength
Price: $79.99
Availability: In Stock
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Revolutionizing
Cosmetic Dermatology
Discover Solvaderm's Professional Strength Products For Healthier And More Beautiful Skin.


Stemuderm is a concentrated anti-aging solution that addresses all of the troublesome signs of skin aging to reduce the appearance of fine lines and restore skin's youthful beauty. Dermatological treatment infused with powerful peptides that may inhibit muscle contractions and prevent unsightly signs of skin aging. Skin-firming complex enhances elasticity while perfecting tone. Revitalizing formula infused with a proven stem cell complex that encouragestotal renewal. Advanced blend of moisturizers quench and soften skin while providing a plumping effect to even out the look of surface irregularities. Skin appears ageless and feels velvety smooth.
DryOily/
CombinationNormalAcne
IssuesRedness
Prone
Stemuderm cares for the entire skin surface while optimizing the production of skin-restructuring compounds in the deeper dermal layer. The following revitalizing properties of Stemuderm make it an advantageous addition to any anti-aging skincare regimen:
- Targets facial structures to discourage repetitive contractions and movements that place stress on skin and keep muscles feeling relaxed
- Stimulates the refortification of the extracellular matrixto make skin appear radically firmer, smoother, and fuller
- Dramatically reduces the visibility of fine lines around the eyes, forehead wrinkles, laugh lines, frown lines, and crow's feet
- Protects and preserves skin with a stem cell therapy complex that helps keep skin looking beautiful and youthful over the long term
- Pampers skin with moisturizers and nutritive conditioners to hydrate skin and noticeably improve texture and softness
Sources To Support The Claims Made For Stemuderm Anti-Wrinkle Treatment
Harder J, Schroder JM. 2005. Psoriatic scales: A promising source for the isolation of human skin derived antimicrobial proteins. J Leucocyte Biol 77:476-486. 8. Harder J, Bartels J, Christophers E, Schroder JM. 1997. A peptide antibiotic from human skin. Nature 387:861. 9. Frohm M, Agerberth B, Ahangari G. 1997. The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders. J Biol Chem 272: 15258-15263. 10. Nilsson MF, Sandstedt B, Sorensen O, Stahle-Backdahl M. 1999. The human cationic antimicrobial protein (hCAP18), a peptide antibiotic, is widely expressed in human squammous epithelia and colocalizes with interlukin 6. Infect Immun 67:2561- 2566. 11. Zaiou M, Nizet V, Gallo RL. 2003. Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J Invest Dermatol 120:810-816. 12. Cowland JB, Johnsen AH, Borregaard N. 1995. hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules. FEBS Lett 368:173-176. 13. Gallo RL, Kim KJ, Bernfield M, Kozak CA, Zanetti M, Merluzzi L. 1997.14. De Y, Chen Q, Schmidt AP, Anderson GM, Wang JM, Wooters J. 2000. LL-37, the neutrophil granule- and epithelial cell derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattractant human peripheral blood neutrophils, monocytes, and T cells. J Exp Med 192:1069-1074.
Purified Water (Aqua), Simmondsia Chinensis (Jojoba) Seed Oil, Prunus Armeniaca (Apricot) Kernel Oil, Squalane, Hyaluronic Acid, Laureth-7, C13-14 Isoparaffin, Polyacrylamide, Acetyl Hexapeptide-8, Pentapeptide-3, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Glutamyl Heptapeptide-1, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide -7, Malus Domestica Fruit Cell Culture, Phenoxyethanol, Ethylhexylglycerin.
Acetyl Hexapeptide-8
This polypeptide made up of naturally occurring amino acids has powerful skin-beautifying capabilities. Its mechanism of action is somewhat similar to that of Neurotoxic (BTA) A, but its effects are milder, and painful injections are not necessary.Acetyl hexapeptide-8works by disrupting specific pathways to inhibit muscle contractions, which can dramatically reduce the appearance of wrinkles. In one study, women who used cream containing this peptide showed an average decrease in apparent wrinkle depth of 27 percent after just 30 days. Some showed decreases of between 50 and 60 percent.
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Dipeptide diaminobutyroyl benzylamide diacetate, also known as SYN-AKE™, acts in a somewhat similar manner as the venom from a snake called the Temple Viper. This Stemuderm ingredient, however, is completely safe, and contains no poisons of any kind. It relaxes facial characteristics, which makes it particularly effective at reducing the appearance and effects of wrinkles caused by repetitive muscle contractions. These kinds of wrinkles include laugh lines, crow's feet, and frown lines. A clinical study found that using SYN-AKE for just 28 days reduced the visibility of forehead wrinkles by up to 52 percent. Participants also showed a dramatic improvement in skin smoothness.
Acetyl Glutamyl Heptapeptide-1
Muscles contract in response to messages sent via proteins by the neurotransmitter acetylcholine, and repeated contractions are one of the main contributing causes of lines, furrows, and wrinkles. Acetyl glutamyl heptapeptide-1has the remarkable ability to disrupt the proteins that carry messages and interrupt the pathway that leads to muscle contractions. This helps keep muscles in a relaxed state, which can dramatically reduce the visibility of wrinkles.
Palmitoyl Oligopeptide
The primary benefit of this peptide is its ability to increase skin's elasticity and make it stronger so it is better able to withstand stress and resist damage. Palmitoyl oligopeptide contains a matrikine, a type of compound that has the astonishing ability to stimulate the repair and renewal of the extracellular matrix. It promotes complete skin revitalization to improve its overall appearance and tone.
Pentapeptide-3& Palmitoyl Tetrapeptide-7 (Matrixyl 3000)
This key Stemuderm ingredient composed of polypeptides has two matrikines that stimulate the production of elastin and hyaluronic acid, both of which are found in abundance in youthful, smooth, firm skin. In a study that lasted just under two months, women who used Matrixyl 3000 showed a 45 percent decrease in the surface area that appeared to be occupied by deep wrinkles. Apparent wrinkle density, depth, and volume were reduced, and subjects also had smoother skin by the end of the study.
Malus Domestica Fruit Cell Culture
The vital component of this rejuvenating serum is stem cells taken from an extremely rare apple found in Switzerland. Various studies have shown these apple cells can protect the stem cells found in human skin, which play a key role in healing and repair. The skin stem cell serum in Stemuderm can combat various signs of skin aging, extend the life cycle of vital cells, and make skin appear more youthful. In a scientific study, 100 percent of participants showed a noticeable reduction in apparent wrinkle depth after just 28 days.
Simmondsia Chinensis (Jojoba) Seed Oil
The most remarkable property of this Stemuderm ingredient is that it is more similar to the oil produced by the skin than any other natural compound on Earth. Aside from being a nourishing moisturizer, this non-greasy ingredient can help curb excess oil production, clear clogged pores, reduce the appearance of fine lines, and make skin softer and suppler.
Prunus Armeniaca (Apricot) Kernel Oil
Derived from the kernel of the familiar apricot fruit, this moisturizer found in Stemuderm has a light, velvety texture that won't make skin feel greasy. This silky oil has many benefits for all types of skin. It hydrates, assists in promoting optimal moisture balance, is believed to have a firming and toning effect, and also helps relieve inflammation and irritation.
Squalane
Squalane is an extract found in olive oil that can noticeably improve the texture and appearance of skin. Squalane not only helps hydrate skin, but also locks in moisture to keep it looking smooth and feeling soft. Along with the other extracts in Stemuderm, it helps make fine lines less noticeable.
Hyaluronic Acid
A compound found naturally in the skin, hyaluronic acid can hold up to 1,000 times its weight in water. One of the most powerful moisturizers currently available, hyaluronic acid has a plumping effect, which helps diminish the appearance of wrinkles and fine lines. It also improves the look and texture of skin by making it appear smoother and more even.
*Disclaimer: The FDA has not evaluated these statements and the supplement product is not intended to diagnose, treat, cure or prevent any disease. Remember to read our labels and ingredient lists carefully and follow the appropriate directions for use. If you have a specific allergy or sensitivity, do not use ingredients that may trigger a reaction. An allergy patch test is recommended if there is any doubt or history of skin reactions. Discontinue use if a reaction occurs.*

After cleansing and toning, apply to face, neck and décolleté. Apply a small amount of Stemuderm to your fingertips and lightly massage with a circular motion into the skin focusing on lines and wrinkled areas. Apply each morning and before bed each night to protect, nourish and maintain hydration. As with any highly effective product, your skin may need time to adjust. Begin applying this product every other day for the first week. After one week, begin following the daily routine.
Important Dispensing Directions - This Product Uses An Airless PumpThis product has an airless pump dispenser which uses a vacuum system to dispense the product. When using your airless pump for the first time, you will need to prime the container by pumping out excess air. To prime your pump, cover the opening where the product comes out of with a finger and at the same time pump slowly about 10-15 times. This will help to push extra air out and get the pump working correctly or "jumpstarted". If at anytime your air pump stops working, simply repeat the priming process.
*Disclaimer: The FDA has not evaluated these statements and the supplement product is not intended to diagnose, treat, cure or prevent any disease. Remember to read our labels and ingredient lists carefully and follow the appropriate directions for use. If you have a specific allergy or sensitivity, do not use ingredients that may trigger a reaction. An allergy patch test is recommended if there is any doubt or history of skin reactions. Discontinue use if a reaction occurs.*
How to Use Stemuderm
Summary Of Customer Ratings & Reviews
- Overall Rating
- Effect
- Performance
- Value
- Texture
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Made a huge difference in texture…
Sarah A. Age: 31-35 -
I love this treatment…
Tracie T. Age: 21-25 -
I'm so glad I switched…
Jenna D. Age: 26-30 -
My complexion glows…
Tara S. Age: 21-25 -
My frown lines are invisible…
Meaghan M. Age: 26-30 -
I use it everywhere…
Jill M. Age: 31-35 -
Entire face feels lifted…
Sharron M. Age: 26-30 -
Really working…
Michelle J. Age: 21-25 -
Helping me keep and improve my youth…
Marjorie D. Age: 31-35I’m only in my 30s but I want to preserve whatever youth I have left in my skin! Living in such a sunny climate means I’m exposed to a LOT of sunlight. This is helping me keep and improve my beautiful skin. Within the first week of using this, the texture of my cheeks and chin were smoother and softer. I don’t want to develop the deeper lines in my forehead so I’ll continue to use this religiously!
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Reduced my "elevens"…
Pam A. Age: 21-25 -
Quite impressed by the benefits…
Kate S. Age: 26-30 -
No more injections…
Danielle L. Age: 36-40 -
Doing great things for my skin…
Connie G. Age: 31-35 -
I love this…
Yvette S. Age: 26-30 -
No more permanent line on my forehead…
Anne P. Age: 21-25 -
I'm glowing…
Roxanna F. Age: 31-35 -
Impressed with how it blurs lines and wrinkles…
Margaret E. Age: 31-35 -
Face feels and looks velvety smooth…
Hallie D. Age: 26-30 -
Some of my wrinkles disappear within minutes…
Jessica F. Age: 21-25 -
I'm seeing great results…
Carol N. Age: 36-40 -
Smooths so beautifully…
Maria N Age: 31-35 -
Great for men too!…
Audra K. Age: 26-30 -
Feels really nice…
Janet W. Age: 21-25 -
My skin has never looked younger…
Andrea N. Age: 26-30 -
I'm very impressed with its effectiveness…
Athena C. Age: 36-40 -
I see a huge improvement…
Andi R. Age: 31-35 -
I can't wait to see even better results the longer I use it…
Kendra W. Age: 21-25 -
My favorite age rewinder…
Jessica O. Age: 36-40 -
Skin feels smooth and soft…
Rebecca W. Age: 31-35 -
People comment on how beautiful my skin looks…
Sandra F. Age: 26-30 -
Onto my second bottle…
Gloria G. Age: 21-25 -
Fills in the lines and wrinkles…
Alyssa F. Age: 41-45 -
I actually look younger…
Martha B. Age: 36-40 -
I look well-rested and radiant!…
Lucy U. Age: 31-35 -
Worked wonders on my skin…
Katie M. Age: 26-30 -
This is worth a try…
Dorinda H. Age: 36-40 -
Smoother forehead…
Louise S. Age: 21-25 -
Firmer, tighter and more lifted…
Keri B. Age: 31-35 -
Healthier plumper skin…
Lindy W. Age: 26-30Since I started using this about a month ago, I have healthier plumper skin, especially around my nose and mouth and cheeks. No dry patches, no irritation, and no redness. What a relief that I don’t have to suffer flaking dry skin to see results.
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I'm getting great results…
Morgan P. Age: 36-40 -
What a difference this has made…
Sharon J. Age: 41-45 -
Very gentle but effective…
Grace G. Age: 31-35 -
My favorite skincare product right now…
Clara H. Age: 21-25 -
Dullness is fading away…
Hope T. Age: 46-50 -
Skin looks healthier and more youthful…
Kathy L. Age: 31-35 -
Immediate improvements…
Stacey S. Age: 36-40 -
I'm a believer now…
Lynette F. Age: 41-45 -
Noticeable difference in lines…
Rebecca B. Age: 41-45 -
Tightening effect…
Suzanne S. Age: 31-35 -
Only moisturizer I need…
Olivia B. Age: 36-40 -
Skin looks truly amazing…
Marta U. Age: 26-30 -
Love the dispenser…
Maria L. Age: 41-45 -
Well worth the money…
Brandi I. Age: 36-40 -
Best anti-wrinkle treatment cream…
Sandra L. Age: 31-35 -
Firmed cheeks and forehead…
Charity R. Age: 26-30 -
Absolutely worth the price…
Alexi B. Age: 36-40 -
Perfect amount of moisture…
Ray-lynn B. Age: 31-35 -
I can tell my skin is plump…
Michelle B. Age: 36-40 -
Seriously amazing!
Ryann A. Age: 41-45 -
Plumping my fine lines…
Ashley P. Age: 36-40 -
Wrinkles are gone…
Noreen W. Age: 46-50 -
Velvety smooth…
Marissa M. Age: 41-45 -
Better than an injection…
Heather A. Age: 31-35 -
My face looks lifted…
Aileen T. Age: 36-40 -
I've been told I look younger…
Marg D. Age: 36-40 -
Nothing bad to say…
Jillian L. Age: 36-40 -
A noticeable difference…
Veenita R. Age: 31-35 -
Bragging rights…
Ella O. Age: 36-40 -
New skin…
Angela N. Age: 41-45 -
More than satisfied…
Allie R. Age: 36-40 -
Better and better…
Jillian C. Age: 36-40 -
Not a day without…
Ali G. Age: 31-35 -
Firm and clear…
Marty E. Age: 31-35 -
Results…
Lisa H. Age: 31-35 -
Big changes…
Amy R. Age: 31-35 -
Radiance booster…
Marci L. Age: 36-40 -
Toned up…
Brianna W. Age: 31-35 -
Looking younger…
Juliette R. Age: 26-30 -
Glowing…
Mindy S. Age: 31-35 -
Much more firm…
Macy H. Age: 36-40 -
It works!…
Cynthia C. Age: 31-35 -
So much improvement…
Karin B. Age: 31-35 -
Years erased!…
Mindy C. Age: 26-30 -
Feeling good…
Doreen I. Age: 26-30 -
Confidence booster…
Audrey D. Age: 31-35 -
Looking younger…
Jordan Z. Age: 26-30 -
Much more firm…
Kirstin F. Age: 31-35 -
Firm, bright and radiant!…
Nan G. Age: 31-35 -
Total transformation…
Sophia R. Age: 36-40 -
Best results!…
Mandy H. Age: 36-40 -
Well rested…
Misty S. Age: 41-45 -
Change for the better…
Hillary E. Age: 41-45 -
Recommended…
Shelly A. Age: 31-35 -
Never looked better…
Chelsea R. Age: 46-50 -
Younger and revived…
Stacey S. Age: Above 50 -
Impressive Results…
Casey W. Age: 36-40 -
Daily dose!…
Sarah B. Age: 41-45 -
Serious transformation…
Amy P. Age: 41-45 -
Young and refreshed!….
Terra C. Age: 46-50 -
Awesome product!…
Taylor C. Age: 41-45 -
Daily dose…
Gina W. Age: 36-40 -
Totally impressed…
Melissa O. Age: 46-50 -
Young again…
Ashley B. Age: 36-40 -
Worth every dime!
Cynthia W. Age: 46-50 -
A change for the better…
Cece J. Age: 36-40 -
Total Transformation!…
Ashley B. Age: 41-45 -
Looking and feeling good…
Cherity R. Age: 31-35 -
Great Product!
Perry D. Age: 41-45 -
Youthful…
Ora G. Age: 36-40 -
Happy customer…
Andrea C. Age: 46-50 -
Transformation…
Jerri D. Age: 36-40 -
Best skin since youth!…
Barbara A. Age: 36-40 -
Changed my skin…
Hillary K. Age: 31-35 -
Facelift in a bottle…
Nancy G. Age: 46-50 -
Won't be without it!…
Bobby S. Age: Above 50 -
Years gone!…
Tori K. Age: 46-50 -
Firm and radiant…
Lisa G. Age: 31-35 -
Brightness is back!…
Liz A. Age: 36-40 -
Short and sweet…
Livy F. Age: Above 50 -
Happy with purchase…
Elizabeth A. Age: 31-35 -
Worth the investment!…
Tori C. Age: 41-45 -
Awesome results!…
Shina S. Age: 36-40 -
Best Product…
Hannah O. Age: 26-30 -
Impressive!…
Rita Z. Age: 31-35 -
Like new!…
Elizabeth H. Age: 31-35 -
More than satisfied…
Olivia Z. Age: 26-30 -
My go to…
Vali S. Age: 21-25 -
Good purchase…
Lydia H. Age: Above 50 -
Impressed…
Jessie R. Age: 46-50 -
Wedding ready!…
Mary W. Age: 26-30 -
Skin balanced…
Sara M. Age: 26-30 -
Is this really me!?…
Pat W. Age: 36-40 -
Miracle in a bottle…
Bobby N. Age: 46-50 -
5 stars!
Hillary M. Age: Above 50 -
Wrinkles gone…
Beth S. Age: 41-45 -
Bought this for my wife…
Mark H. Age: 46-50 -
Miracle Product!
Carly S. Age: 31-35 -
My kids notice…
Andrea J. Age: 41-45 -
Former smoker…
Cindy A. Age: 31-35 -
Keeper!
Nancy G. Age: 36-40 -
My partner loves it.
Ellen A. Age: 26-30 -
Long lasting results.
Karen S. Age: 26-30 -
Perfect cover.
Elizabeth E. Age: 31-35 -
Great product but expensive
Linda S. Age: 41-45I can see noticeable difference on my forehead and laugh lines. This product provided elasticity to my skin and it goes a long way.
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BEST ANTI-AGING PRODUCT
Jarlyn S. Age: 46-50 -
Pleasant Surprise.
Sandra B. Age: 31-35 -
This is it!
Tracy M. Age: 31-35 -
So far – so good
Susan B. Age: 41-45 -
Feels Fantastic on Skin
Jaxquiline R. Age: 26-30 -
Glowing
Becca W. Age: 36-40 -
Really works…
Ollie D. Age: 31-35 -
Loving it.
Mitchell S. Age: 31-35
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For Best Results
Combine Stemuderm with these products to achieve the best results.
Fine lines look like they were erased…
My forehead lines became very noticeable so I found this recently. I’ve been using it for 3 months now, and now in pictures my forehead lines look like they were erased. This treatment is excellent!